Glade Run is managed under the Commission's Big Bass program. Channel catfish fingerling are stocked to supplement the warmwater species found in the lake.
The Commission stocks Glade Run with trout a number of times throughout the year. Statewide regulations for Commonwealth Inland Waters apply for all other species of fish.
A fishing pier is available for persons with disabilities.
Boating is limited to boats powered by electric motors and un-powered boats. There is a surfaced launch ramp and associated parking facilities.
Un-powered boats may be moored at the lake in accordance with Commission property regulations. To be used at the lake, boats must be registered or have a valid launch permit (permits are issued by the Commission or PA Dept. of Conservation and Natural Resources).